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These findings, along with ongoing research, suggest that GLP-1 medications hold significant promise for managing NAFLD/NASH and preventing complications such as cirrhosis and liver failure

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This shifts clinical emphasis toward interventions with stronger evidence for preserving lean masssuch as adequate dietary protein and resistance trainingwhile complementary biological modulators like postbiotics may improve insulin sensitivity and inflammatory tone, thereby supporting metabolic resilience rather than directly increasing thermogenesis

Effects of CPAP on body weight in patients with obstructive sleep apnoea: a meta-analysis of randomised trials