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During the follow-up period (median 27.5 mo), 469 patients died (353 [10.8%] in the untreated group, 116 [1.4%] in the DAA-treated group), 586 developed hepatocellular carcinoma (343 [10.5%] in the untreated group, 243 [2.9%] in the DAA-treated group), 580 developed decompensation (372 [11.4%] in the untreated group, 208 [2.5%] in the DAA-treated group), and 18 underwent liver transplantation (8 [0.2%] in the untreated group, 10 [0.1%] in the DAA-treated group)

Because these two proteins largely determine the mechanical behavior of skin its resistance to stretching and its ability to recoil the practical implication for GHK-Cu skin research is direct and measurable