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This double delay leads to food sitting in the stomach longer, creating more gas and fermentation, and eventually causing discomfort and often stomach pressure

While current research focuses predominantly on hepatocytes, potential Kupffer cell modulation in NASH-related inflammation and fibrosis warrants further investigation (78)

It is going to be important to pull apart whether it is obesity management or direct cellular pathwaysindependent of glucose-loweringleading to a positive impact on these cardiovascular risk factors