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La hiptesis propone que estas bacterias podran modular la microbiota intestinal, reducir la inflamacin de bajo grado y potencialmente estimular las clulas enteroendocrinas para aumentar la produccin de GLP-1 endgeno, posiblemente a travs de cidos grasos de cadena corta o sealizacin de cidos biliares
The efficacy and safety of setmelanotide in individuals with Bardet-Biedl syndrome or Alstrm syndrome: phase 3 trial design
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Wegovy: Starts at 0.25mg weekly and increases every 4 weeks Typical maintenance dose: 1.7mg or 2.4mg Mounjaro: Starts at 2.5mg weekly, then increases in 2.5mg steps Maximum dose: 15mg weekly Both drugs require gradual dose escalation (titration) to allow the body to adapt and reduce the risk of side effects
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