a ch: 138A Ging V - Ba nh- H Ni - Vit Nam [email protected] Gii thiu Tin tc Phng nga bnh i tho ng Bnh i Tho ng Chung sng vi bnh i tho ng i tho ng tr em i tho ng thanh thiu nin i tho ng ngi trng thnh i tho ng ngi cao tui i tho ng ph n mang thai Tm Hiu V H ng Huyt Nghin cu khoa hc v o to Trong nc D tho Din n Hi p cng chuyn gia Hng dn s dng bt tim thuc ng vn th th GLP-1 V CHNG TI CC QUN L KHM CHA BNH-B Y T a ch:138A Ging VBa nhH NiVit Nam inthoi:(+84-024) 62732445 Fax:(+84-024) 62732289 Email: [email protected] Website c xy dng vi s h tr ca
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(11)Fmoc-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin (11) Preparation of Fmoc-Pro-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin (10)Fmoc-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin(20DMF)5203DMF3DMF2Fmoc-Pro-OH0.8gDIEA0.4mlTBTU0.56gHOBT0.2gDMF10ml1.53DMF3DMF2Fmoc-Pro-Gly-Lys(Boc)-Pro- Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin In step (10) of Fmoc-Gly-Lys(Boc)-Pro-Ala-Asp(otBu)-Asp(otBu)-Ala-Gly-Leu-Val-WangResin, add decapping reagent (20% piperidine in DMF solution), reacted at room temperature for 5 minutes, drained, added decapping agent and reacted at room temperature for 20 minutes, washed 3 times with isopropanol, washed 3 times with DMF, washed 2 times with re-distilled DMF, drained, added Fmoc-Pro- 0.8g of OH, 0.4ml of DIEA, 0.56g of TBTU, 0.2g of HOBT, and 10ml of DMF were reacted at room temperature for 1.5 hours, dried with a vacuum pump, washed 3 times with isopropanol, washed 3 times with DMF, washed 2 times with distilled DMF, pumped Dry, obtain Fmoc-Pro-Gly-Lys (Boc)-Pro-Ala-Asp (otBu)-Asp (otBu)-Ala-Gly-Leu-Val-WangResin

Injection Site Reactions Prevalence: Common Symptoms: Redness, itching, or swelling at the injection site