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Although N-acetylcysteine (NAC) directly influences the pool of extracellular cystine and intracellular cysteine via a series of plasmatic redox reactions, in order to be effective, intracellular cysteine precursors must be designed to enter erythrocytes rapidly and use high activity enzymes within erythrocytes to liberate cysteine (Whillier et al., 2009
Insulin-like growth factor-1 regulates the SIRT1-p53 pathway in cellular senescence
Innes JF, Fuller CJ, Grover ER, Kelly AL, Burn JF
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