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Patients with pre-existing gastrointestinal conditions, such as peptic ulcer disease or gastro-oesophageal reflux disease (GORD), should exercise particular caution

The semaglutide component has an established safety profile from over 7 years of post-marketing experience

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This means: Growth hormone releasing peptides (GHRPs), growth hormone releasing hormone (GHRH) analogs, and similar compounds like CJC-1295 and Ipamorelin are banned at all times. (WADA Prohibited List 2024) Athletes tested by organizations like USADA or Olympic federations will fail doping controls if using either compoundeven when used off-season