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But heres the catch: a large 2026 systematic review of the NAD+ research looking at over a hundred human and animal studies found zero controlled trials proving IV or injectable NAD+ actually improves anti-aging or wellness outcomes in otherwise healthy people
The drug increased the likelihood of achieving at least 5% body weight loss but was associated with higher rates of mild-to-moderate gastrointestinal side effects
Dramatic or rapid changes in skin color are not associated with healthy glutathione use
Injecting cold solution, injecting too rapidly, or using a dull needle all increase pain regardless of site
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