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The R package MaAsLin2 [40] was used to carry out the multivariable associations, thanks to which the eventual correlations between metagenomic data and treatment or phenotype were assessed, whilst considering the false discovery rate
Additional processing may be required.
In addition, Serine and arginine rich splicing factor 9 (SFRS9) can upregulate the expression of GPX4 by binding to GPX4 mRNA, which promote the growth of CRC, while SFRS9 knockdown significantly inhibited tumor growth in nude mice (Wang R
& Aikawa, M
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