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However, the VABS-II behavioral assessment, demonstrated significant changes only in children receiving CRWP compared to those observed in the placebo group in the composite score (effect size 0.98
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MAMs are essential for the regulation of the neuronal Ca 2+ concentration via the SERCA, the ER channels inositol 1,4,5-trisphosphate receptors, the glucose-regulated protein 75, the MCU, and the voltage-dependent anion channel (VDAC) [61]
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Increased total sleep time by ~59% vs placebo in a controlled study
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