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High-dose systemic ascorbic acid may cause renal oxalate stones and hemolytic anemia in susceptible individuals

Follow with Moisturizer and Sunscreen: For optimal results, follow up with a moisturizer to lock in hydration and a broad-spectrum sunscreen with SPF 30 or higher to protect your skin from harmful UV rays

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Practical Considerations Titration may be needed: Starting lower and building up could minimize GI side effects