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Cancers (Basel) 13, 843

(N=18 type-2 diabetic patients, many of whom had early CKD) found no significant changes in creatinine clearance, cystatin C, or urinary albumin:creatinine ratio with creatine 5 g/day compared to placebo

Key Research Insight Tesamorelin: Associated with more consistent and sustained IGF-1 elevation in controlled studies Supported by both clinical and preclinical data Ipamorelin: Can influence IGF-1 indirectly via GH pulses Effects may be less stable and more model-dependent Research Applications of Tesamorelin and Ipamorelin 1