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Ascorbate, dithiothreitol and TCEP reduce copper(II) to copper(I), and the donor set that stabilizes the divalent ion does not stabilize the monovalent one, so the complex is destroyed and the released copper becomes redox-active

Small interfering RNA targeting of S phase kinase-interacting protein 2 inhibits cell growth of oral cancer cells by inhibiting p27 degradation

Discovery of selective and potent macrocyclic cdk9 inhibitors for the treatment of osimertinib-resistant non-small-cell lung cancer

It also helps reduce cell damage in the liver (such as that from alcohol consumption, especially if taken beforehand)