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Specifically, confidence is considered high if supportive evidence derives from multiple RCTs and observational studies, medium if the evidence derives from conflicting RCTs or compelling observational studies, and low if the evidence derives from observational studies only
Otherwise, patients will discuss the treatment plan with their provider including diet and exercise changes, possible side effects, and proper administration
The prescribing note should include: the patient's current HbA1c or BMI with date of measurement, a chronological list of all prior therapies with dates and reasons for discontinuation, a statement of why liraglutide specifically is preferred over other non-preferred agents (for example, the cardiovascular outcome benefit documented in LEADER [5] for a patient with known coronary artery disease), and a direct reference to the applicable ADA or Endocrine Society guideline recommendation [6][8]
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