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3 These polar elements participate in hydrogen bonding and electrostatic interactions within the receptor binding pocket, while surrounding lipophilic regions promote favorable pharmacokinetics and sustained GLP-1 receptor engagement. Basically, the drug developers ensured that part of the molecule is attracted to water, which helps the body absorb the medicine through the gastrointestinal tract
Infection stage annotation was based on marker genes from Gene Expression Omnibus (GEO) dataset GSE150484
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