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El mecanismo de accin incluye varios efectos fisiolgicos importantes : estimulan la liberacin de insulina cuando los niveles de glucosa en sangre estn elevados, suprimen la secrecin de glucagn (una hormona que aumenta el azcar en sangre), retrasan el vaciamiento gstrico y reducen el apetito actuando sobre los centros de saciedad en el cerebro

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Most of these symptoms improve over time as the body adapts, but they can be significant enough to cause discontinuation in some patients

The results were perhaps associated with the feedback inhibition of proteases in the duodenum according to Li et al