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This is called spectrum bias in which the sensitivity and specificity of a particular cut point is dependent on prevalence

CrossRef Emerging evidence supports direct-acting antiviral therapy for HCC patients beyond the early stage: Correspondence to editorial on Direct-acting antiviral therapy for patients with HCV-related hepatocellular carcinoma: A nationwide cohort study Teng-Yu Lee, Pei-Chien Tsai, Shou-Wu Lee, Ming-Lung Yu Clinical and Molecular Hepatology .2026

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To view or add a comment, sign in More Relevant Posts - : For drugs absorbed mainly in the upper GI tract, rapid gastric emptying can limit exposure