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Despite its efficacy in cancer treatment, the clinical use of DOX is significantly constrained by its severe toxicities on off-target organs (Kalender et al., 2005

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doi: 10.3389/fimmu.2024.1440313 Received 30 May 2024 Accepted 18 November 2024 Published 05 December 2024 Volume 15 - 2024 Edited by Xing Wang, The Affiliated Hospital of Southwest Medical University, China Reviewed by Christoph Hudemann, Philipps-University Marburg, Germany Franziska Roth-Walter, University of Veterinary Medicine Vienna, Austria Updates Copyright 2024 Biedrzycki, Wolszczak-Biedrzycka, Dorf and Maciejczyk