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Among these, HSPA1 is a strongly heat-inducible member that is highly expressed following heat stress (Maugeri et al., 2010)

It acts primarily at the injury site: it upregulates growth hormone receptor expression locally, drives angiogenesis via VEGF, activates the nitric oxide system, and switches on the CREB pathway, the cellular trigger for repair gene expression

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3 When considering whether to pursue assisted reproductive techniques, it is worth bearing in mind that these procedures come with known and theoretical risks