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Slow metabolism
The peptide's immunomodulatory effects include enhancement of T-lymphocyte proliferation in the thymus and increased production of interferon gamma, supporting immune system resilience particularly in aged organisms
However, when tirzepatide is taken together with certain other diabetes medications, it may increase the risk of hypoglycemia
It mitigated pyroptotic responses through modulation of the SIRT1/NOX4/ROS axis, thereby preventing gasdermin-dependent pore formation and cytokine overproduction (Yu et al., 2019)
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