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In cancer cell lines, the mTORC1 signal can also promote de novo lipid synthesis through the sterol responsive element-binding protein (SREBP) transcription factors, which induce the expression of metabolic genes responsible for lipid biosynthesis, including fatty acid synthase (FASN) (Duvel et al., 2010)
They have other downsides too
People with Type 2 Diabetes: GLP1 receptor agonists improve insulin secretion and lower glucagon levels, making them highly effective for managing blood sugar
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