Its believed to promote musculoskeletal repair by upregulating growth factors, stimulating the formation of new blood vessels, or modulating nitric oxide synthesis, but no mechanism of action has been proven.34 TB4, however, has known mechanisms by which it speeds recovery from injury: inhibiting inflammation, preventing cell death, and (as suspected with BPC) promoting blood vessel formation.35 On top of the benefits for physical recovery, the ability to form new blood vessels points to promising implications for cardiovascular health
Understanding long-term outcomes and weight regain One critical question that neither CagriSema nor tirzepatide has fully answered is what happens after treatment stops
Vegans and "patients with diseases like Crohn's and colitis as well as people with pernicious anemia are also particularly vulnerable to deficiency," added Silverstein
In another study, an 84-week open-label trial with about 800 participants, people taking CagriSema had an average of 23% weight loss versus about 25 to 26% for tirzepatide (Zepbound) at the highest dose