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Glutathione is synthesized intracellularly, and while it can be effluxed from a cell it tends to be hydrolyzed to its constituent amino acids to then be taken back up by cells and resynthesized intracellularly into Glutathione

Remote ischemic preconditioning plays a neuroprotective role in cerebral ischemia-reperfusion mice by inhibiting mitophagy

To further confirm this potential shift in the conformational equilibrium, we collected a second cryo-EM dataset for Cagri-CTR ( N = 2) from a separate protein purification