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Recent studies shows that GLP-1 receptor agonists are effective adjuncts to metformin for managing type 2 diabetes mellitus, especially for patients aiming to prevent weight gain or hyperglycemia

Given that the kidney-protective effects of SGLT2 inhibitors are independent of glucose lowering [51], DAPA-CKD and EMPA-KIDNEY have included participants both with and without diabetes mellitus (Table 1, Fig

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