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L-Carnitine and its short-chain esters do not bind to plasma proteins and, although blood cells contain L-carnitine, the rate of distribution between erythrocytes and plasma is extremely slow in whole blood

While the role of GLP-1RA on AMD is still being debated, this study shows a protective effect of GLP-1RA on nonexudative AMD development compared to other antihyperglycemic agents

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It is not however, a FDA approved pharmaceutical