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doi: 10.1016/j.yexcr.2010.08.011 145 OkaniwaNSasakiMMizushimaTOgasawaraNFunakiYJohTet al

The folate cycle and methionine cycle are two major components of this network required for regulating amino acid homeostasis, including the three amino acids that make up glutathione: cysteine, glycine, and glutamic acid