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doi: 10.1007/s11357-020-00282-1 90 WangY.JinS.SonobeY.ChengY.HoriuchiH.ParajuliB.et al

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Recent studies have explored small-molecule inducers, selenium-based compounds, and targeted nanodelivery approaches to restore GPX4 function or mimic its antioxidant capacity in ferroptosis-prone diseases, with therapeutic implications for OA and beyond (26)

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GLP-1, for example, does exactly this

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