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If more than 4 days have passed, skip the missed dose and take the next one on the usual day
So, we recommend using SL vitamin B12 rather than oral and IM, especially in patients who do not tolerate IM injection and patients who need prolonged vitamin B12 supplementation, such as patients with long-term metformin use and patients with pernicious anemia or with gastro-duodenal resection [51,52,53,54]
It is essential to consider alternative explanations for spotting, including gynaecological conditions, hormonal changes related to weight loss itself, or unrelated health issues
Supplementation (with very conservative doses) may be beneficial for those carrying the risk T allele of C667T or the risk C allele of A1298C
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