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This studys novelty lies in proving that functional cognitive improvement can occur via completely opposite transcriptomic profiles

Genome sequencing of 39 Akkermansia muciniphila isolates reveals its population structure, genomic and functional diverisity, and global distribution in mammalian gut microbiotas

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Non-pharmacological approaches form the foundation of ADHD management and include: Psychoeducation for patients and families about ADHD, its impact, and management strategies Environmental modifications such as structured routines, organisational aids, and minimising distractions Cognitive behavioural therapy (CBT) to address comorbid anxiety, depression, or low self-esteem Parent training programmes for children and adolescents with ADHD Occupational therapy to develop practical coping strategies Pharmacological treatment is recommended when ADHD symptoms cause significant impairment despite environmental modifications