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Melatonin enhances antioxidative enzyme gene expression (CAT, GPx, SOD), prevents their UVR-induced depletion, and protects against the formation of DNA damage (8-hydroxy-2-deoxyguanosine) in ex vivo human skin

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Contact your provider right away if you have: Redness spreading more than ~2 inches Increasing pain, warmth, or swelling Red streaks from the site Fever or chills Pus or drainage Signs of severe allergic reaction (hives, trouble breathing, facial swelling) Prevent it: rotate sites weekly, use proper technique, and let the medication reach room temperature first

D., Zdravkovic, M., & Moerch, U