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It is essential to emphasise that any use of GLP-1 medications in Hashimoto's patients would be off-label unless the individual also meets criteria for type 2 diabetes or obesity treatment according to the medication's SmPC

This interaction was further corroborated by pull-down assays and confocal imaging, indicating direct binding between exendin 939 and TRPV1 channels

Approximately 10 mg of liver tissue was homogenized in Qiazol lysis buffer, and RNA was extracted using MiRNeasy Micro Kit (50) (QIAGEN Cat #74104)

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