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The experiment was divided into sham surgery group, I/R model group, and I/R+IGF-1 LR3 treatment group (0.5mg/kg, orally administered 30 minutes before reperfusion)
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However, in line with the potential neuroprotective effect of GLP-1R agonists in ischemic stroke, Rigshospitalet Denmark is running a randomized clinical trial of exenatide as an organ protecting agent, e.g., a brain-protecting agent, where stroke is one of the primary outcome measures (NCT02673931)
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