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This trial followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline and was conducted in compliance with Declaration of Helsinki
Vitamin E adds the benefits of antioxidants 1
Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme
In both male and female GHRKO mice, disruption of the GH/IGF-1 axis from birth results in mice that are remarkably long lived, but temporal disruption of this pathway in young adults (aGHRKO mice) improves lifespan only in females 17 , an observation which is consistent with the beneficial effects of targeting IGF-1R signaling post-development on female healthspan and aging in this study
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