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The mechanisms that may contribute to the induction of oxidative damage in diabetic patients include hyperglycemia-induced glucose auto-oxidation, non-enzymatic glycation of proteins and lipids, increased sorbitol pathway activity, oxidation of AGEs, and formation of prostaglandin H2 (PGH2) [311]
NRF2 inducers, like sulforaphane modify cysteine sensors of Keap1 and inactivate its repressor function
Depending on the dose and other factors, carnitine may make you sweat because it can increase energy expenditure and supports the function of brown adipose tissue, a site of metabolic thermogenesis
