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Mitochondria are cholesterol-poor organelles compared to plasma membrane, and this regulated transport of cholesterol in mitochondria plays physiological role in the synthesis of bile acids in liver and steroidogenic hormones in other tissues
Review Article Abstract Introduction Retatrutide for Treatment of Obesity Retatrutide for Treatment of Type 2 Diabetes Effects of Retatrutide on Cardiovascular Risk Factors Safety of Retatrutide Effect of Retatrutide on Heart Rate Advantages of Retatrutide Limitations of Retatrutide Conclusions and Current Needs References Safety of Retatrutide In the 2 phase 2 trials, 16-17% discontinued retatrutide compared with 0-4% with placebo due to adverse effects (Table 1) [3,4]
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