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Most healthcare providers follow established clinical protocols when managing dose progression for investigational compounds, prioritizing patient safety and gradual adaptation over speed

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Western blot analysis revealed that sulforaphane alone did not obviously alter the expression of mTOR signalling components, but was highly resistant to the inhibition of phosphorylation of mTOR, p70S6K and 4E-BP1 by rotenone, in both the cerebral cortex and striatum (Fig