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#MASH #Hepatology #MetabolicHealth #GLP1 To view or add a comment, sign in Narrative review proposes pancreatic exocrine fibrosis and profibrotic signalling as key drivers of type 3c diabetes, with a potential role in type 2 and type 1 diabetes, and summarises unanswered questions & suggests potential novel therapeutic targets To view or add a comment, sign in We are very grateful to Diabetologia for inviting us to review the growing evidence supporting a profibrotic signalling cycle involving stellate cells, macrophages and islet endocrine cells themselves in the pathogenesis of pancreatogenic diabetes including diabetes associated with pancreatic cancer
IGF-1 is so crucial to human development that studies performed on pubertal children found that high levels of serum IGF-1 were directly correlated to higher bone mineral acquisition later on in life [14, 15]
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