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In any case, the most acknowledged cytoplasmic protein able to regulate NRF2 by promoting its stability and nuclear role is p62 [196]
One study found that patients who switched from a GLP-1 medication to phentermine were 29 percent less likely to regain all of their lost weight compared to patients who stopped GLP-1 treatment entirely without any replacement medication
*Correspondence: Jing Yao, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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