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The most common cause of bradycardia is degeneration of the conduction system due to aging
Despite promising Phase 2 results and an excellent safety profile, the compound could not demonstrate sufficient efficacy in the larger confirmatory trial to justify the investment required for continued pharmaceutical development toward regulatory approval
doi: 10.7554/eLife.48448 246 DemeyerAVan NuffelEBaudeletGDriegeYKreikeMMuyllaertDet al
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