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Ramsey LB, Balis FM, OBrien MM, Schmiegelow K, Pauley JL, Bleyer A, Widemann BC, Askenazi D, Bergeron S, Shirali A, Schwartz S, Vinks AA, Heldrup J (2018) Consensus guideline for use of glucarpidase in patients with high-dose methotrexate induced acute kidney injury and delayed methotrexate clearance

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History of hormone-sensitive conditions As a precaution, until more human data is available

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Recommended initial dosage is amlodipine 5 mg and valsartan 160 mg once daily in those who are not volume depleted

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