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GLP-1 is secreted primarily by L-cells in the distal small intestine and colon

When you eat less food, you consume fewer electrolytes

As we look at Food and Beverage Service and Production Companies, we need to look at the impact of GLP-1s as they bring caloric reduction due to the feeling of satiety and reduction in gastrointestinal transit time

Besides releasing melatonin into the circulation in small amounts (usually levels are in the range of pg/mL), melatonin is also discharged directly into the cerebrospinal fluid (CSF) of the third ventricle and is likely an important primary secretory pathway since the nocturnal elevation in this fluid is roughly an order of magnitude greater than that in the blood ( Figure 1 ) (45)