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The delays in wound healing of aging have widespread clinical and economic impacts, thus novel strategies to improve wound healing in aging are needed and targeting senescence may be a promising area
In the mitochondria, LC is converted to ALC, and balances the acetyl CoA/CoA ratio to maintain glucose metabolism through the TCA cycle, yielding a higher energy production [34]
Experimental Biology and Medicine 2003
J Biol Chem 282:3045265, PMID: 17724027 Ji L, Shen K, Jiang P, Morahan G, Wang Z (2011) Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells
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