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Multiple in vitro studies have demonstrated that NAC actively induces the non-immunological degranulation of mast cells, causing them to dump pre-formed histamine directly into the bloodstream, which can trigger immediate allergic-type symptoms
Some people use oral tablets, gummies, liquids, or sublingual products
Together, they address both local and systemic healing needs
Complementary evidence is provided by another systematic review and metaanalysis by Berg et al
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