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Compared with active drugs, oral semaglutide was superior to empagliflozin in reducing total cholesterol and LDL [36] and was superior to sitagliptin in reducing total cholesterol, LDL, and TAGs [37, 41], but there was no significant difference when compared with another GLP-1 analogue (liraglutide) [38]
This alternative is quickly metabolized by the liver, thereby reducing corticosteroid-related side effects, and appears to be as effective as prednisone, says Bedford
A 2024 study in Frontiers of Endocrinology showed a significant relationship between GLP-1 drugs and several mental health-related adverse events: Stress Eating disorders Fear of injections Sleep disorders Binge eating Fear of eating Self-induced vomiting Other concerns regarding mental health and GLP-1 drugs include questions about impacts on neurotransmitters and whether the same effects that decrease food noise may decrease enjoyment of different activities
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