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The key clinicopathologic indicators of AD are amyloid plaques formed by amyloid accumulation in extracellular regions or hyperphosphorylated Tau proteins aggregated in intracellular regions, which form neural protofibrillary tangles (NFTs) in affected neurons
Roberts DR, Albrecht MH, Collins HR, Asemani D, Chatterjee AR, Spampinato MV, et al
In most of the tissues studied, except for the testis and cerebellum, rTLs were inversely associated with age
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