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Two 2013 systematic reviews of interventions concluded that the modest benefit of propionyl-L-carnitine on walking performance was equivalent or superior to that obtained with drugs approved for claudication in the US (e.g., pentoxyphylline, cilostazol) yet inferior to improvements seen with supervised exercise interventions (69, 70)

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Liu Y, Ren L, Ge L, Cui Q, Cao X, Hou Y, et al

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These data instill optimism about the impact that this drug might have in the treatment of T2DM and its complications in every day clinical practice

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It is a crucial element for several metalloenzymes involved in redox functions

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