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Under extreme iodine exposure, the thyroid gland may also exhibit aberrant expression of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its death receptor (DR)-5, resulting in follicular cell apoptosis
References Maar K, Hetenyi R, Maar S, Faskerti G, Hanna D, Lippai B, Takatsy A, Bock-Marquette I
It is unproven whether BPC-157 causes receptor downregulation in humans
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