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Administering an MT-1-sized dose of MT-2 would be a significant overdose and would likely lead to pronounced side effects like intense nausea, facial flushing, and other unwanted systemic responses
A 2021 systematic review of 16 randomized controlled trials and 6,276 participants (Markun and colleagues, Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue, Nutrients, 2021) found that B12 supplementation does not reliably reduce fatigue in people who are not deficient
Ensure adequate protein intake: Aim for 1.2 to 1.6g of protein per kilogram of body weight daily to preserve lean muscle mass during weight loss
With the finding of weight loss, manufacturers studied higher doses and entered applications for use of the chemical entities for weight loss products
