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Tissue sections were incubated with primary antibodies (4-HNE, abcam, #ab46545, 1:5000, rabbit and CCR2, abcam, ab273050, 1:200, rabbit) diluted in 1% BSA in PBS and incubated at 4 C overnight
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The supply of NADPH is essential to regenerate GSH and dictates the rate of H 2 O 2 reduction by Gpx while keeping the reduced status of mitochondria
TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation
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