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Notably, at higher doses (such as 12 mg once weekly), mean weight loss exceeding 20% of body weight was observed in adults with obesity over approximately 48 weeks

[33] Another open-label study that used glutathione containing lozenges reported improvement in the skin melanin index, as measured by Mexameter [Table - 1]

The drug may aggravate abdominal symptoms in patients with inflammatory bowel disease, notably ulcerative colitis